When a man is found dead in a San Diego motel, minus his leg, police initially believe it's the result of a car accident. But evidence soon casts suspicion on the involvement of Dr. John Brown, an underground gender reassignment surgeon.

November 22, 1998 - Dr. Jack Kevorkian assists the death of a terminally ill patient live on TV. Kevorkian is tried for murder, and the nation is split. Is Kevorkian a saint who helps end patients' suffering, or a crack-pot who loves the limelight?

When Samira Frasch is found dead at the bottom of the pool, police begin to investigate her podiatrist husband. Did he stage the scene to hide his crime? Or could someone else spotted by a witness be to blame?

The suicide of a Maryland beauty queen leaves her loved ones in shock. But when her sister turns detective, she finds evidence that suggests Sara has not died by her own hand. Detectives set about proving who is guilty of her murder.

Police are called to a shooting in the town of Wenham, Massachusetts. Mother of three, Karen Sharpe dies later that night. But who would want to kill her? Investigators soon uncover Karen is in the midst of a multi-million dollar divorce.

At Delmenhorst Hospital, Germany, administrators notice death rates in their intensive care unit have risen sharply. Suspicions fall on nurse Niels Hogel, who turns out to be Germany's most prolific murderer since WWII.

When a resident dies at a care home in Albany, Western Australia, it's assumed she passed away peacefully. But an autopsy reveals horrific injuries. In the frame is carer Jacob Hoysted, but can this quiet, young man really be a brutal murderer?

When an elderly care home resident is discovered dead, staff members sense that something is amiss. A murder investigation begins into a nurse at the home, but when she becomes a victim of violent attacks, could someone else be responsible?

A modus operandi that mimics natural death works to the advantage of a north Texas serial killer who preys on elderly victims. His murderous death toll is suspected of having amounted to 22 before a sinister clue leads to his capture.

Motivated by greed, a small-town Oklahoma doctor writes a prescription for death, flooding her community with a lethal cocktail of drugs, and leaving a trail of victims in her wake.