A lava monster attacks Jace on Jupiter (incorrectly depicted as a cratered rocky planet). Space Ghost must save him from the monster. A tribe of worm-like creatures captures Dino Boy and Ugh must plan a rescue. Zorak, one of Space Ghost's enemies, is freed from prison by his henchmen and kidnaps the twins in a revenge plot against Space Ghost.

After suffering a reactor burnout, Jan and Jace land on a planet where huge animals live and are controlled by the Creature King. Dino Boy is captured by a group of Treemen to serve as a sacrifice and Ugh must leap into action with the help of some mammoths. Lizard-like slavers capture Jan and Jace for stumbling across their base.

The Black Widow plans to kill Space Ghost with her minions, the Tarantopods, on her planet. Ugh is captured by the Sun People to serve as a sacrifice and Dino Boy must stop them. Metallus threatens to destroy Earth with a missile unless Space Ghost surrenders to him.

A mysterious figure uses a robot to steal the Phantom Cruiser. Space Ghost and the twins must retrieve it. While running from a T-rex, Dino Boy and Ugh are captured by the Moss Men after falling into a water-filled hole that leads to their lair. The Moss Men plan to use Dino Boy as a sacrifice. Ugh must defeat the Moss Men and rescue Dino Boy before it is too late. The Sandman has attacked military units to draw Space Ghost to him in order to destroy his mind and conquer the world.

Metallus uses a robot fleet to take over Space Ghost's planet. As Dino Boy teaches Ugh how to spell, they are attacked by venomous wasps who sting Ugh. Dino Boy must get some choka leaves from Misty Island or Ugh will die. At the same time, he must stop two Moss Men from sacrificing one of their own. Space Ghost must fight a monster created by Dr. Soonev in a lab accident.

Jan and Jace are captured by Tansit after they witness his hi-jacking of a ship. While running from a volcanic eruption, Dino Boy ends up in a valley of giants. He has to run from giant ants and Ugh must come to the rescue. Brak kidnaps Jan so that Space Ghost will not interfere in his robbery plans.

Space Ghost is ensnared in the Schemer's plan to kill the team. Dino Boy and Bronty get in trouble with a Smilodon and are separated. Bronty is captured by the Rock Pygmies and Dino Boy must save him while leaving markers to show Ugh where he went. The Collector shrinks people to use in a real-life cat-and-mouse game involving his pet six-legged alien cat Dracto.

Lokar lures the twins to him to be captured by his killer locust robots. After rescuing a kid from some Birdmen, Dino Boy and Ugh row along the Danger River to bring him home, where they encounter various threats like the Snake People and dangerous river rapids. Brago's bandits attack an outpost and the twins must defend them until Space Ghost arrives.

Space Ghost must rescue the twins from Cyclo and his robots. A Fire God captures Dino Boy. The Saber-Tooth People plan to sacrifice him, but Ugh is determined to foil them. The Lurker and his partner One Eye have been preying on ships that pass close by and now they have their sights set on the Phantom Cruiser.

Zeron attacks Space Ghost by using a powerful ice ray. While showing off his kite invention to Ugh, Dino Boy ends up crashing into the mountains and ends up captured by the Vampire Men. Jace's time machine invention accidentally sends Jan back in time, where she is taken captive by a Viking named Tarko the Terrible. When Jace also gets captured trying to save her, it is up to Space Ghost to rescue them.

An evil genius is using metal birds to attack satellites and destroy them. Ugh is captured by the Wolf People. Dino Boy and Bronty must save him. Space Ghost must defeat a UFO from another galaxy that could be acting as a vanguard for an invasion.

Dr. Nightmare is planning on taking Space Ghost's brain for his mechanical monsters. During an earthquake, Bronty is captured by a giant and Dino Boy and Ugh must save him. Space Ghost and the twins must stop Metallus' new, powerful missiles.

The twins and Space Ghost are forced to battle Zorket and his rock robots. Dino Boy and Ugh are forced to protect a Bird Rider from the Rock Pygmies. Space Ghost and the twins must stop Metallus' new, powerful missiles.

The Mind Taker is abducting people to steal their knowledge. Dino Boy teaches Ugh how to shoot a bow and arrow and Ugh throws his club at a rock but it was revealed to be a T-rex who attacks them. After that, a Pteranodon kidnaps Dino Boy for food and Ugh must save him. Staying true to her word, the Black Widow/the Spider Woman tries to kill Space Ghost again. This time, she uses aquatic creatures.

The Creature King is planning on using his monsters to conquer Jupiter. Space Ghost must prevent the mastermind from reaching that goal. The Sun People are hunting and start chasing Ugh. Dino Boy must save him. Glasstor captures the twins in order to force them to work in his glass mines.

Piranor wants to use his space piranhas to take revenge on Space Ghost. Dino Boy and Ugh are collared for attacking a Spear Warrior and have to fight their way out. Transor plans on using Jan and Jace as specimens in his zoo.

The Sorcerer is using his powerful magic for evil and plans to challenge Space Ghost. Ugh is captured by the Ant Warriors after fighting a Stegosaurus and got away. Dino Boy tries to rescue him but ends up having to save the Ant Warriors from a Megatherium. Brak is using sleeping gas to rob gold shipments and Space Ghost has to stop them.

Moltor is planning on using his molten men and ships to take over the universe. Dino Boy and Ugh venture into the snow-capped mountains to rescue a young tribal girl from a large Snow Creature. Space Ghost must keep the Gargoyloids, who have inhabited a planet during their wanderings through space, from causing problems in the galaxy.

Metallus, the Creature King, Zorak, Moltar, Brak, and the Black Widow/the Spider Woman unite to form the Council of Doom as they plan to destroy Space Ghost. Metallus goes first and uses a fleet of robots to attack Space Ghost. After defeating Metallus, Space Ghost is forced to land on the Creature King's world. Cameos by Tor/Mighty Mightor and Tog. After Space Ghost thwarts the Creature King, Zorak plans to destroy Space Ghost using monsters.

After escaping Zorak, Space Ghost and the twins are captured by Moltar. Cameos by Zandor, Tara, Dorno, and The Herculoids. Following Moltar's defeat, Brak and the Black Widow/the Spider Woman each take their turns to dispose of Space Ghost. Space Ghost, Jan, Jace and Blip take the final fight to the Council of Doom. Cameos by Shazzan, Chuck, Nancy, and Kaboobie. This was also the only episode to have villains not associated with the Council of Doom, the Sultan of the Flame and his Fire Demon.